Post-translational modifications (PTMs) of histones exert fundamental roles in regulating gene expression.During development, groups of PTMs are constrained by unknown mechanisms into combinatorial patterns, which facilitate transitions from uncommitted embryonic cells into differentiated somatic cell lineages.Repressive histone modifications such
The implementation of safer drug consumption facilities in Scotland: a mixed methods needs assessment and feasibility study for the city of Edinburgh
Abstract Background Scotland currently has amongst the highest rates of drug-related deaths in Europe, leading to increased advocacy for safer drug consumption facilities (SDCFs) to be piloted in the country.In response to concerns about drug-related harms in Edinburgh, elected officials have considered introducing SDCFs in the city.This paper pres
The use of dendrograms to describe the electrical activity of motoneurons underlying behaviors in leeches
The present manuscript aims at identifying patterns of electrical activity recorded from neurons of the leech nervous system, characterizing specific behaviors.When leeches are at rest, the electrical activity of neurons and motoneurons is poorly correlated.When leeches move their head and/or tail, in contrast, action potential (AP) firing becomes
Characterization of ceramic waste filled unsaturated polyester resin for domestic applications
In this work an unsaturated polyester resin (UPR) containing porcelain powder prepared from ceramic waste were fabricated and Lotion subjected to various studies.The mechanical properties, thermal stability, and water absorption resistance of the UPR and composites prepared for each condition were evaluated.Results show that porcelain powder based
Cross-vendor programming abstraction for diverse heterogeneous platforms
Hardware specialization is a well-known means to significantly improve the performance and energy efficiency of various application domains.Modern computing systems consist of multiple specialized processing devices which need to Shirts collaborate with each other to execute common tasks.New heterogeneous programming abstractions have been created